Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.42 |
| ▸ | MAOA | P21397 | 9/20 | 0.42 |
| ▸ | KDM1A | O60341 | 9/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30141969 | 1.00 | MAOB (0.42) | MAOBMAOAKDM1ACYP2C19CYP2B6 | |
| Trifluoroacetic Acid SCHEMBL29891929 | 0.86 | KDM1A (0.43) | KDM1ASLC6A2 | |
| Tert-Butyl Formate SCHEMBL28065029 | 0.83 | TDP1 (0.34) | MAOBMAOAKDM1ACYP2C19CYP2B6 | |
| SCHEMBL15580371 | 0.78 | SLC18A3 (0.55) | SLC6A2SLC18A3SIGMAR1CHRNB2CHRNA4 | |
| SCHEMBL4237630 | 0.78 | SLC18A3 (0.55) | SLC6A2SLC18A3SIGMAR1CHRNB2CHRNA4 | |
| SCHEMBL24233804 | 0.77 | MEN1 (0.43) | SLC6A2ADRA1ASLC6A3SLC18A3SIGMAR1 | |
| SCHEMBL17066472 | 0.77 | MEN1 (0.43) | SLC6A2ADRA1ASLC6A3SLC18A3SIGMAR1 | |
| SCHEMBL5054915 | 0.77 | SLC18A3 (0.39) | CYP2C19CYP1A2CYP2D6CYP2C9CYP2A6 | |
| SCHEMBL22473177 | 0.77 | MEN1 (0.43) | SLC6A2ADRA1ASLC6A3SLC18A3SIGMAR1 | |
| SCHEMBL22473203 | 0.77 | SLC18A3 (0.39) | KDM1ACYP2C19CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275749-A1 | PRODUCTION METHOD OF OPTICALLY ACTIVE PIPERAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-11-05 | — | — | US | disclosed |
| EP-1930325-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE PIPERAZINE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275749-A1 | PRODUCTION METHOD OF OPTICALLY ACTIVE PIPERAZINE COMPOUND | CYP51A1, CYP4Z1, CYP4A11 | MAOB 119/4885MAOA 139/4885KDM1A 674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.