Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 7/20 | 0.30 |
| ▸ | MAOA | P21397 | 6/20 | 0.30 |
| ▸ | KDM1A | O60341 | 5/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30141969 | 0.83 | MAOB (0.42) | MAOBMAOAKDM1ACYP2C19CYP2B6 | |
| SCHEMBL13629823 | 0.83 | MAOB (0.42) | MAOBMAOAKDM1ACYP2C19CYP2B6 | |
| Tert-Butyl Formate SCHEMBL28065009 | 0.81 | KDM1A (0.34) | TDP1MAOBMAOAKDM1ASLC6A2 | |
| Tert-Butyl Formate SCHEMBL28065028 | 0.78 | CFB (0.33) | MAOBMAOAKDM1A | |
| Tert-Butyl Formate SCHEMBL27790496 | 0.77 | TDP1 (0.37) | TDP1TAAR1 | |
| Trifluoroacetic Acid SCHEMBL29891929 | 0.77 | KDM1A (0.43) | KDM1ASLC6A2 | |
| Tert-Butyl Formate SCHEMBL28064897 | 0.75 | PRCP (0.36) | TDP1LMNA | |
| Tert-Butyl Formate SCHEMBL28209963 | 0.74 | PRCP (0.35) | TDP1KDM1A | |
| Tert-Butyl Formate SCHEMBL28803048 | 0.72 | TDP1 (0.35) | TDP1MAOBMAOAKDM1ACYP2C19 | |
| Tert-Butyl Formate SCHEMBL27488567 | 0.72 | SLC18A3 (0.62) | TDP1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579444-B | Piperidinylindole derivatives and their use as complement factor B inhibitors | 诺华股份有限公司 | 2018-05-01 | — | — | CN | disclosed |
| CN-105579444-A | Piperidinylindole derivatives and their use as complement factor B inhibitors | NOVARTIS AG | 2016-05-11 | — | — | CN | disclosed |