Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 9/20 | 0.49 |
| ▸ | USP2 | O75604 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | RORA | P35398 | 3/20 | 0.42 |
| ▸ | RORC | P51449 | 3/20 | 0.42 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | OSBP | P22059 | 1/20 | 0.39 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.39 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13521627 | 0.84 | NPC1L1 (0.48) | NPC1L1USP2LMNAMEN1KMT2A | |
| SCHEMBL13521591 | 0.78 | NPC1L1 (0.66) | NPC1L1USP2LMNAMEN1KMT2A | |
| SCHEMBL13629830 | 0.77 | NPC1L1 (0.46) | NPC1L1USP2LMNAMEN1KMT2A | |
| SCHEMBL13521634 | 0.76 | NR1H3 (0.46) | LMNAMEN1KMT2ANR1H3 | |
| SCHEMBL13523224 | 0.75 | NPC1L1 (0.47) | NPC1L1USP2LMNAMEN1KMT2A | |
| SCHEMBL14611856 | 0.72 | NR1H3 (0.60) | NPC1L1USP2LMNAMEN1KMT2A | |
| SCHEMBL13629834 | 0.72 | CDC25A (0.57) | NPC1L1USP2LMNAMEN1KMT2A | |
| SCHEMBL14597020 | 0.71 | NPC1L1 (0.43) | NPC1L1USP2LMNAMEN1KMT2A | |
| SCHEMBL29339071 | 0.71 | NPC1L1 (0.60) | NPC1L1USP2LMNAMEN1KMT2A | |
| SCHEMBL13521629 | 0.70 | GABRA1 (0.39) | NPC1L1USP2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275064-A1 | Methods to identify therapeutic agents | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275064-A1 | Methods to identify therapeutic agents | MSR1, SCARB1, LDLR | NPC1L1 161/4885USP2 3911/4885LMNA 2214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.