Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 4/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 7/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13629830 | 0.86 | NPC1L1 (0.46) | CDC25AIGF1RMETSRCAXL | |
| SCHEMBL13521632 | 0.84 | CDC25A (0.57) | CDC25AGABRA1GABRB1GABRG2GABRB3 | |
| SCHEMBL13630375 | 0.79 | CDC25A (0.78) | CDC25AGABRA1GABRB1GABRG2GABRB3 | |
| SCHEMBL13521601 | 0.79 | CDC25A (0.78) | CDC25AGABRA1GABRB1GABRG2GABRB3 | |
| SCHEMBL3134063 | 0.79 | CDC25A (0.78) | CDC25AGABRA1GABRB1GABRG2GABRB3 | |
| SCHEMBL3134072 | 0.79 | CDC25A (0.78) | CDC25AGABRA1GABRB1GABRG2GABRB3 | |
| SCHEMBL13629833 | 0.72 | NPC1L1 (0.49) | SRD5A1SRD5A2USP2NPC1L1RORA | |
| SCHEMBL13521639 | 0.70 | NPC1L1 (0.48) | CDC25AIGF1RMETSRCAXL | |
| SCHEMBL13521630 | 0.70 | NPC1L1 (0.48) | CDC25AIGF1RMETSRCAXL | |
| SCHEMBL13521645 | 0.68 | GABRA1 (0.50) | CDC25AGABRA1GABRB1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275064-A1 | Methods to identify therapeutic agents | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275064-A1 | Methods to identify therapeutic agents | MSR1, SCARB1, LDLR | CDC25A 3921/4885GABRA1 2267/4885GABRB1 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.