Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.62 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.53 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13616315 | 1.00 | SENP1 (0.62) | SENP1AMY1AKMT2AMEN1NPC1 | |
| SCHEMBL4341594 | 1.00 | SENP1 (0.62) | SENP1AMY1AKMT2AMEN1NPC1 | |
| SCHEMBL4351015 | 1.00 | SENP1 (0.62) | SENP1AMY1AKMT2AMEN1NPC1 | |
| SCHEMBL4351018 | 1.00 | SENP1 (0.62) | SENP1AMY1AKMT2AMEN1NPC1 | |
| SCHEMBL4341599 | 1.00 | SENP1 (0.62) | SENP1AMY1AKMT2AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL4348249 | 0.99 | SENP1 (0.61) | SENP1AMY1AKMT2AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL4348254 | 0.99 | SENP1 (0.61) | SENP1AMY1AKMT2AMEN1NPC1 | |
| SCHEMBL13630355 | 0.88 | KMT2A (0.54) | SENP1AMY1AKMT2AMEN1NPC1 | |
| SCHEMBL13746768 | 0.87 | SENP1 (0.57) | SENP1AMY1AKMT2AMEN1NPC1 | |
| SCHEMBL13616349 | 0.87 | MEN1 (0.49) | SENP1AMY1AKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275538-A1 | ARYLMETHYLIDENE HETEROCYCLES AS NOVEL ANALGESICS | UNIVERSITE LAVAL (CA) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275538-A1 | ARYLMETHYLIDENE HETEROCYCLES AS NOVEL ANALGESICS | OPRL1, OPRK1, AHR | SENP1 4049/4885AMY1A 3049/4885KMT2A 1752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.