Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14189783 | 0.87 | ALDH1A1 (0.59) | ALDH1A1KCNH2HTR2AHTR2CMAPT | |
| SCHEMBL9500234 | 0.86 | HTR2A (0.64) | ALDH1A1KCNH2HTR2AHTR2CSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9501491 | 0.84 | HTR2A (0.62) | ALDH1A1KCNH2HTR2AHTR2CSMN1; SMN2 | |
| SCHEMBL12859265 | 0.84 | KMT2A (0.64) | ALDH1A1KCNH2HTR2AHTR2CMAPT | |
| SCHEMBL11402919 | 0.82 | ADRA1A (0.64) | KCNH2HTR2AKMT2AMEN1SIGMAR1 | |
| SCHEMBL17430893 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KCNH2HTR2AHTR2CMAPT | |
| SCHEMBL12424250 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KCNH2HTR2AHTR2CMAPT | |
| SCHEMBL12384479 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KCNH2HTR2AHTR2CMAPT | |
| SCHEMBL4875267 | 0.81 | ALDH1A1 (0.79) | ALDH1A1KCNH2HTR2AHTR2CMAPT | |
| SCHEMBL4308106 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KCNH2HTR2AHTR2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |