Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | WNT1 | P04628 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27365079 | 0.85 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1LMNAPOLBTP53 | |
| SCHEMBL5482515 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1WNT1GSK3BDYRK1A | |
| SCHEMBL13136035 | 0.82 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1TERTTDP1GAA | |
| SCHEMBL23291308 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1WNT1GSK3BDYRK1A | |
| SCHEMBL1965586 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1WNT1GSK3BDYRK1A | |
| SCHEMBL2663389 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1POLBTP53MEN1 | |
| SCHEMBL26891587 | 0.81 | WNT1 (0.42) | SMN1; SMN2ALDH1A1WNT1GSK3BDYRK1A | |
| SCHEMBL28164677 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1TERTLMNATSHR | |
| SCHEMBL13629917 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1TERTLMNATSHR | |
| SCHEMBL27272041 | 0.80 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1LMNAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |