SCHEMBL13630653

SCHEMBL13630653

CC(C)Oc1cc(O)cc(/C=C/c2ccc(O)cc2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.67
CYP1A1 P04798 5/20 0.67
CYP1B1 Q16678 4/20 0.67
TTR P02766 3/20 0.67
ALOX5 P09917 3/20 0.67
KDM4E B2RXH2 5/20 0.60
PTGS1 P23219 5/20 0.60
MEN1 O00255 4/20 0.60
MAPT P10636 4/20 0.60
KMT2A Q03164 4/20 0.60
CYP1A2 P05177 3/20 0.60
ALDH1A1 P00352 3/20 0.60
LMNA P02545 3/20 0.60
TP53 P04637 3/20 0.60
CYP3A4 P08684 3/20 0.60
HPGD P15428 3/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
HSD17B10 Q99714 3/20 0.60
CA12 O43570 3/20 0.60
CA1 P00915 3/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13630652 0.86 PTGS1 (0.65) PTGS2CYP1A1CYP1B1TTRALOX5
SCHEMBL25612270 0.81 TTR (0.70) PTGS2CYP1A1CYP1B1TTRALOX5
SCHEMBL562336 0.80 CYP1A1 (1.00) PTGS2CYP1A1CYP1B1TTRALOX5
SCHEMBL30475363 0.80 CYP1A1 (1.00) PTGS2CYP1A1CYP1B1TTRALOX5
SCHEMBL562335 0.80 CYP1A1 (1.00) PTGS2CYP1A1CYP1B1TTRALOX5
Resveratrol SCHEMBL27998695 0.79 PTGS1 (0.95) PTGS2CYP1A1CYP1B1TTRALOX5
SCHEMBL7192552 0.79 CYP1A1 (0.54) PTGS2CYP1A1CYP1B1TTRALOX5
SCHEMBL7192549 0.79 CYP1A1 (0.54) PTGS2CYP1A1CYP1B1TTRALOX5
SCHEMBL2470272 0.79 APP (0.57) PTGS2CYP1A1CYP1B1TTRALOX5
SCHEMBL13587590 0.77 PTGS2 (0.69) PTGS2CYP1A1CYP1B1TTRALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013037985-A1 PHARMACEUTICAL COMBINATIONS INCLUDING ANTI-INFLAMMATORY AND ANTIOXIDANT CONJUGATES USEFUL FOR TREATING METABOLIC DISORDERS GENMEDICA THERAPUTICS SL (ES) 2013-03-21 WO disclosed
WO-2009138437-A1 SALICYLATE CONJUGATES USEFUL FOR TREATING METABOLIC DISORDERS GENMEDICA THERAPEUTICS SL (ES) 2009-11-19 WO disclosed