SCHEMBL562335

SCHEMBL562335

COc1cc(O)cc(/C=C/c2ccc(O)cc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 6/20 1.00
CYP1B1 Q16678 6/20 1.00
PTGS2 P35354 5/20 1.00
ALOX5 P09917 5/20 1.00
TTR P02766 4/20 1.00
KDM4E B2RXH2 5/20 0.89
NQO2 P16083 5/20 0.89
MEN1 O00255 4/20 0.89
MAPT P10636 4/20 0.89
KMT2A Q03164 4/20 0.89
ABL1 P00519 4/20 0.89
BCR P11274 4/20 0.89
PTGS1 P23219 3/20 0.89
ABCB1 P08183 3/20 0.89
NPC1 O15118 2/20 0.89
GAA P10253 2/20 0.89
RAB9A P51151 2/20 0.89
GFER P55789 2/20 0.89
HDAC6 Q9UBN7 2/20 0.89
MAPK1 P28482 1/20 0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30475363 1.00 CYP1A1 (1.00) CYP1A1CYP1B1PTGS2ALOX5TTR
SCHEMBL562336 1.00 CYP1A1 (1.00) CYP1A1CYP1B1PTGS2ALOX5TTR
Pterostilbene SCHEMBL563218 0.94 CYP1A1 (1.00) CYP1A1CYP1B1PTGS2ALOX5TTR
Pterostilbene SCHEMBL28222684 0.94 CYP1A1 (1.00) CYP1A1CYP1B1PTGS2ALOX5TTR
Pterostilbene SCHEMBL3545782 0.94 CYP1A1 (1.00) CYP1A1CYP1B1PTGS2ALOX5TTR
Pterostilbene SCHEMBL20063 0.94 CYP1A1 (1.00) CYP1A1CYP1B1PTGS2ALOX5TTR
SCHEMBL2516449 0.92 PTGS2 (0.86) CYP1A1CYP1B1PTGS2ALOX5TTR
SCHEMBL2516446 0.92 PTGS2 (0.86) CYP1A1CYP1B1PTGS2ALOX5TTR
SCHEMBL29652111 0.92 PTGS2 (0.86) CYP1A1CYP1B1PTGS2ALOX5TTR
SCHEMBL29662231 0.92 PTGS2 (0.86) CYP1A1CYP1B1PTGS2ALOX5TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743071-A2 DIPHENYLETHYLENE COMPOUNDS AND COMPOSITIONS THEREOF INNOVENE INC. (US) 2026-05-20 EP claimed
EP-4687856-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS Therapeutics, LLC (US) 2026-02-11 EP claimed
CN-120000585-A Novel drug-assisted precursor micelle preparation and production method thereof 酰莱(合肥)生命科学研发有限公司 2025-05-16 CN claimed
CN-119506313-A Methyltransferase gene for catalyzing methylation of resveratrol and application thereof 广西科学院 2025-02-25 CN claimed
WO-2025015023-A2 DIPHENYLETHYLENE COMPOUNDS AND COMPOSITIONS THEREOF INNOVENE, INC. (US) 2025-01-16 WO claimed
WO-2024229159-A2 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS THERAPEUTICS, LLC (US) 2024-11-07 WO claimed
US-20240366525-A1 GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING JDS THERAPEUTICS, LLC 2024-11-07 US claimed
CN-118389548-A SbOMT3 gene mutant for directionally constructing and efficiently converting resveratrol into pterostilbene and pinostilbene, and preparation method and application thereof 浙江工业大学 2024-07-26 CN claimed
CN-115768739-B Aqueous solution containing stilbene compound and superoxide generation inhibitor containing stilbene compound 益冈典芳 2024-03-01 CN claimed
US-20240026314-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS ROTHSTEIN STEVEN (CA) 2024-01-25 US claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
CN-115768739-A Aqueous solution containing stilbene compound and superoxide generation inhibitor containing stilbene compound 益冈典芳 2023-03-07 CN claimed
CN-115197114-A Aromatic selenium cyanogen ester compound and green synthesis method and application thereof 南宁师范大学 2022-10-18 CN claimed
CN-114903927-A Medicine for preventing and treating hepatic fibrosis and preparation method thereof 盐城师范学院 2022-08-16 CN claimed
WO-2022109736-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS ROTHSTEIN STEVEN (CA) 2022-06-02 WO claimed
CN-111657042-B Planting method for promoting formation of pterocarpus indicus heartwood 中国林业科学研究院资源昆虫研究所 2021-12-03 CN claimed
CN-111657042-A Planting method for promoting formation of pterocarpus indicus heartwood 中国林业科学研究院资源昆虫研究所 2020-09-15 CN claimed
CN-107417532-B Resveratrol acrylic acid phenolic ester derivative and preparation method and application thereof 合肥工业大学 2020-07-10 CN claimed
US-20120178704-A1 PREVENTION AND TREATMENT OF COLON CANCER RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2012-07-12 US claimed
WO-2008070872-A1 PREVENTION AND TREATMENT OF COLON CANCER RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2008-06-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120178704-A1 PREVENTION AND TREATMENT OF COLON CANCER APC, SI, NFKBIA CYP1A1 1123/4885CYP1B1 1133/4885PTGS2 28/4885
US-20240026314-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS COMT, PNMT, GNMT CYP1A1 340/4885CYP1B1 461/4885PTGS2 3010/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.