Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13630707 | 1.00 | HIF1A (0.33) | HIF1AHSD17B10KMT2ATARDBPTSHR | |
| SCHEMBL754554 | 0.74 | HSD17B10 (0.58) | HIF1AHSD17B10KMT2ATARDBPTSHR | |
| SCHEMBL8521624 | 0.74 | HSD17B10 (0.58) | HIF1AHSD17B10KMT2ATARDBPTSHR | |
| SCHEMBL9358814 | 0.74 | EPHX1 (0.38) | ALDH1A1 | |
| SCHEMBL29249729 | 0.73 | HSD17B10 (0.56) | HIF1AHSD17B10KMT2ATARDBPTSHR | |
| SCHEMBL29249658 | 0.73 | HSD17B10 (0.56) | HIF1AHSD17B10KMT2ATARDBPTSHR | |
| SCHEMBL6039759 | 0.73 | — | — | |
| SCHEMBL7711923 | 0.72 | EPHX1 (0.41) | TSHRALDH1A1THRB | |
| SCHEMBL14039354 | 0.72 | HLCS (0.33) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL14976125 | 0.72 | EPHX1 (0.41) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140683-A1 | LIVING COPOLYMER PROTEIN/PEPTIDE HYBRIDS FOR BIOMEDICAL APPLICATIONS | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2009-11-19 | — | — | WO | disclosed |