Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434350 | 1.00 | REN (0.45) | RENPDE4BHTR1AADRA1DHTR2A | |
| SCHEMBL13434352 | 0.90 | PDE4B (0.50) | RENPDE4BHTR1AADRA1DHTR2A | |
| SCHEMBL13630935 | 0.90 | PDE4B (0.50) | RENPDE4BHTR1AADRA1DHTR2A | |
| SCHEMBL3489210 | 0.89 | REN (0.48) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL13434298 | 0.89 | REN (0.45) | RENPDE4BHTR1AADRA1DHTR2A | |
| SCHEMBL13434587 | 0.89 | REN (0.43) | RENPDE4BHTR1AADRA1DHTR2A | |
| SCHEMBL13631036 | 0.89 | REN (0.43) | RENPDE4BHTR1AADRA1DHTR2A | |
| SCHEMBL13434381 | 0.89 | REN (0.43) | RENPDE4BHTR1AADRA1DHTR2A | |
| SCHEMBL13434393 | 0.88 | REN (0.44) | RENPDE4BHTR1AADRA1DHTR2A | |
| SCHEMBL13630937 | 0.88 | REN (0.44) | RENPDE4BHTR1AADRA1DHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |