Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13630906 | 0.95 | TSHR (0.44) | TSHRALDH1A1RECQLGAAEPHX2 | |
| SCHEMBL13630898 | 0.86 | TSHR (0.50) | TSHRALDH1A1RECQLGAAEPHX2 | |
| SCHEMBL10092236 | 0.81 | TSHR (0.57) | TSHRALDH1A1RECQLGAAEPHX2 | |
| SCHEMBL26200750 | 0.78 | TSHR (0.53) | TSHRALDH1A1RECQLGAAEPHX2 | |
| SCHEMBL13630895 | 0.76 | TSHR (0.52) | TSHRALDH1A1RECQLGAAEPHX2 | |
| SCHEMBL18997736 | 0.76 | TSHR (0.50) | TSHRALDH1A1RECQLGAAEPHX2 | |
| SCHEMBL4881440 | 0.75 | TSHR (0.50) | TSHRALDH1A1RECQLGAAEPHX2 | |
| SCHEMBL13630904 | 0.75 | TSHR (0.46) | TSHRALDH1A1RECQLGAAEPHX2 | |
| SCHEMBL11382562 | 0.72 | TSHR (0.65) | TSHRALDH1A1RECQLGAAEPHX2 | |
| SCHEMBL13630893 | 0.71 | POLB (0.61) | ALDH1A1GAAPOLBSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |