Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5837295 | 0.89 | HPGD (0.39) | TSHRALDH1A1HPGDGAAKMT2A | |
| SCHEMBL4881902 | 0.84 | ALDH1A1 (0.54) | TSHRALDH1A1HPGDGAAKMT2A | |
| SCHEMBL301433 | 0.83 | TSHR (0.51) | TSHRALDH1A1HPGDGAAKMT2A | |
| SCHEMBL302645 | 0.81 | MAPT (0.50) | TSHRALDH1A1RECQLHPGDGAA | |
| SCHEMBL617437 | 0.81 | MAPT (0.43) | TSHRALDH1A1RECQLHSD17B10EPHX2 | |
| SCHEMBL10092236 | 0.81 | TSHR (0.57) | TSHRALDH1A1RECQLHPGDGAA | |
| SCHEMBL5836968 | 0.79 | PTGS1 (0.49) | ALDH1A1GAAKMT2APOLBSMN1; SMN2 | |
| SCHEMBL26200750 | 0.78 | TSHR (0.53) | TSHRALDH1A1RECQLHPGDGAA | |
| SCHEMBL14889325 | 0.78 | TSHR (0.47) | TSHRALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL2159807 | 0.77 | L3MBTL1 (0.61) | TSHRALDH1A1RECQLHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293821-A1 | Cooling compositions | MOZA ASHOK K | 2008-11-27 | — | — | US | disclosed |
| US-20080038386-A1 | Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition | MOZA ASHOK K | 2008-02-14 | — | — | US | disclosed |
| US-20080038386-A1 | Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition | MOZA ASHOK K | 2008-02-14 | — | — | US | disclosed |
| US-7030273-B1 | Compounds with physiological cooling effect | QAROMA, INC (US) | 2006-04-18 | — | — | US | disclosed |