Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13630908 | 0.80 | RECQL (0.47) | POLBSMN1; SMN2TDP1KDM4ELMNA | |
| SCHEMBL6188978 | 0.80 | LMNA (0.55) | POLBTDP1LMNAALDH1A1KMT2A | |
| SCHEMBL13255792 | 0.76 | HDAC3 (0.47) | POLBKDM4ELMNAALDH1A1KMT2A | |
| SCHEMBL4039186 | 0.74 | ALDH1A1 (0.83) | POLBSMN1; SMN2TDP1KDM4ELMNA | |
| SCHEMBL10092236 | 0.73 | TSHR (0.57) | POLBSMN1; SMN2TDP1KDM4ELMNA | |
| SCHEMBL11159885 | 0.72 | POLB (0.48) | POLBSMN1; SMN2KDM4ELMNAALDH1A1 | |
| SCHEMBL13630898 | 0.71 | TSHR (0.50) | POLBSMN1; SMN2TDP1KDM4ELMNA | |
| SCHEMBL13630894 | 0.71 | TSHR (0.50) | POLBSMN1; SMN2TDP1KDM4ELMNA | |
| SCHEMBL10595824 | 0.71 | LMNA (0.68) | POLBSMN1; SMN2TDP1KDM4ELMNA | |
| SCHEMBL26200750 | 0.71 | TSHR (0.53) | POLBSMN1; SMN2TDP1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |