Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17119221 | 0.79 | CYP2C19 (0.36) | ALDH1A1KMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL5733012 | 0.78 | TSHR (0.38) | ALDH1A1KMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL25075398 | 0.77 | KDM4E (0.46) | KDM4ELMNAMAPK1ALDH1A1GAA | |
| SCHEMBL23136900 | 0.76 | KDM4E (0.35) | KDM4ELMNAMAPK1HTTALDH1A1 | |
| SCHEMBL7067353 | 0.74 | KDM4E (0.44) | KDM4ELMNAMAPK1ALDH1A1GAA | |
| SCHEMBL11259548 | 0.74 | TSHR (0.52) | ALDH1A1TSHR | |
| SCHEMBL2225315 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL7792166 | 0.72 | TSHR (0.50) | LMNAALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL12137187 | 0.72 | ALDH1A1 (0.41) | KDM4ELMNAMAPK1HTTALDH1A1 | |
| SCHEMBL1421256 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |