Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948452 | 1.00 | HSD11B1 (0.48) | HSD11B1ALDH1A1GAACPB1TSHR | |
| SCHEMBL8097829 | 1.00 | HSD11B1 (0.48) | HSD11B1ALDH1A1GAACPB1TSHR | |
| SCHEMBL30736145 | 1.00 | HSD11B1 (0.48) | HSD11B1ALDH1A1GAACPB1TSHR | |
| SCHEMBL8097832 | 1.00 | HSD11B1 (0.48) | HSD11B1ALDH1A1GAACPB1TSHR | |
| SCHEMBL13434301 | 1.00 | HSD11B1 (0.48) | HSD11B1ALDH1A1GAACPB1TSHR | |
| SCHEMBL25438608 | 1.00 | HSD11B1 (0.48) | HSD11B1ALDH1A1GAACPB1TSHR | |
| SCHEMBL1722459 | 0.92 | PDE4B (0.51) | HSD11B1ALDH1A1GAACPB1TSHR | |
| SCHEMBL2218999 | 0.92 | ALDH1A1 (0.56) | HSD11B1ALDH1A1GAATSHRCTSL | |
| SCHEMBL29232309 | 0.89 | ALDH1A1 (0.53) | HSD11B1ALDH1A1GAATSHRCTSL | |
| SCHEMBL25072073 | 0.88 | HSD11B1 (0.48) | HSD11B1ALDH1A1GAACPB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |