Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 9/20 | 0.62 |
| ▸ | MGAM | O43451 | 7/20 | 0.62 |
| ▸ | AMY1A | P0DUB6 | 7/20 | 0.62 |
| ▸ | SI | P14410 | 7/20 | 0.62 |
| ▸ | MGAM2 | Q2M2H8 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281090 | 0.82 | GAA (0.58) | TP53GAAMGAMAMY1ASI | |
| SCHEMBL29625506 | 0.81 | GAA (0.73) | TP53GAAMGAMAMY1ASI | |
| SCHEMBL361654 | 0.81 | GAA (0.73) | TP53GAAMGAMAMY1ASI | |
| Hydrochloric Acid SCHEMBL1371916 | 0.80 | GAA (0.71) | TP53GAAMGAMAMY1ASI | |
| SCHEMBL2490943 | 0.79 | TP53 (0.67) | TP53GAAMGAMAMY1ASI | |
| SCHEMBL5285726 | 0.78 | TP53 (0.59) | TP53GAAMGAMAMY1ASI | |
| SCHEMBL14303694 | 0.78 | TP53 (0.59) | TP53GAAMGAMAMY1ASI | |
| SCHEMBL12093975 | 0.77 | GAA (1.00) | TP53GAAMGAMAMY1ASI | |
| SCHEMBL11583708 | 0.77 | KDM4E (0.57) | EGLN3NPC1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL11524883 | 0.76 | GAA (0.67) | TP53GAAMGAMAMY1ASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615573-B2 | Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-11-10 | — | — | US | disclosed |
| US-20070203223-A1 | Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203223-A1 | Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors | UGCG, UGGT1, DPAGT1 | TP53 4846/4885GAA 91/4885MGAM 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.