Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.68 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1365741 | 1.00 | GPR35 (0.68) | GPR35SCDRARBMEN1ALDH1A1 | |
| SCHEMBL1157009 | 1.00 | GPR35 (0.68) | GPR35SCDRARBMEN1ALDH1A1 | |
| SCHEMBL1158480 | 1.00 | GPR35 (0.68) | GPR35SCDRARBMEN1ALDH1A1 | |
| SCHEMBL17985022 | 0.91 | GPR35 (0.59) | GPR35MAPTPPARA | |
| SCHEMBL12487331 | 0.87 | GPR35 (0.87) | GPR35RARBMEN1ALDH1A1RARA | |
| SCHEMBL9948994 | 0.87 | GPR35 (0.66) | GPR35BIDMCL1BCL2L1BAK1 | |
| SCHEMBL1030733 | 0.82 | GPR35 (0.64) | GPR35SCDRARBMEN1ALDH1A1 | |
| SCHEMBL1157118 | 0.82 | GPR35 (0.49) | GPR35MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1157064 | 0.82 | GPR35 (0.49) | GPR35MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1365121 | 0.82 | GPR35 (0.49) | GPR35MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571888-B1 | METHODS OF MAKING FUSED THIOPHENES | CORNING INC (US) | 2014-12-31 | — | — | EP | disclosed |
| EP-2571888-A1 | METHODS OF MAKING FUSED THIOPHENES | Corning Incorporated (US) | 2013-03-27 | — | — | EP | disclosed |
| US-8217183-B2 | Methods of making fused thiophenes | CORNING INCORPORATED (US) | 2012-07-10 | — | — | US | disclosed |
| US-20110288306-A1 | METHODS OF MAKING FUSED THIOPHENES | CORNING INCORPORATED | 2011-11-24 | — | — | US | disclosed |
| WO-2011146308-A1 | METHODS OF MAKING FUSED THIOPHENES | CORNING INCORPORATED (US) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288306-A1 | METHODS OF MAKING FUSED THIOPHENES | DCX, TST, GNPAT | GPR35 2757/4885SCD 2051/4885RARB 2043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.