Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | ERN1 | O75460 | 4/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307694 | 0.85 | TUBB4A (0.53) | PTPN1ERN1ALDH1A1CYP2C9HSD17B10 | |
| SCHEMBL13632014 | 0.82 | TUBB4A (0.46) | PTPN1ERN1TAAR1ALDH1A1TUBB4A | |
| SCHEMBL1306882 | 0.77 | TUBB4A (0.48) | PTPN1ERN1ALDH1A1CYP2C9TUBB4A | |
| SCHEMBL13632046 | 0.73 | PTPN1 (0.47) | PTPN1ERN1TAAR1ALDH1A1HDAC1 | |
| SCHEMBL13631988 | 0.71 | TUBB4A (0.60) | ERN1ALDH1A1CYP2C9HSD17B10TUBB4A | |
| SCHEMBL1306366 | 0.70 | TUBB4A (0.56) | ALDH1A1CYP2C9HSD17B10TUBB4ATUBB | |
| SCHEMBL1308350 | 0.70 | TUBB4A (0.52) | PTPN1ERN1ALDH1A1CYP2C9HSD17B10 | |
| SCHEMBL13632012 | 0.70 | TUBB4A (0.48) | PTPN1ERN1ALDH1A1CYP2C9TUBB4A | |
| SCHEMBL13632020 | 0.69 | PTPN1 (0.46) | PTPN1ERN1ALDH1A1HDAC1KEAP1 | |
| SCHEMBL13632067 | 0.68 | TUBB4A (0.51) | PTPN1ERN1ALDH1A1CYP2C9HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275575-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275575-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | TUBB1, TUBA1C, TUBB6 | PTPN1 2954/4885ERN1 2333/4885TAAR1 4409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.