Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9611200 | 0.68 | APP (1.00) | APPMAPTMEN1NPC1KMT2A | |
| SCHEMBL864945 | 0.68 | APP (1.00) | APPMAPTMEN1NPC1KMT2A | |
| SCHEMBL28719719 | 0.67 | APP (0.74) | APPMAPTMEN1NPC1KMT2A | |
| SCHEMBL21903463 | 0.64 | APP (0.88) | APPMAPTMEN1NPC1KMT2A | |
| SCHEMBL18763506 | 0.63 | APP (1.00) | APPMAPTMEN1NPC1KMT2A | |
| SCHEMBL10035461 | 0.63 | APP (0.74) | APPMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28765066 | 0.62 | APP (0.57) | APPMAPTMEN1NPC1KMT2A | |
| SCHEMBL27701520 | 0.62 | APP (0.56) | APPMAPTMEN1NPC1KMT2A | |
| SCHEMBL3122121 | 0.62 | APP (0.72) | APPMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13299891 | 0.61 | APP (0.61) | APPMAPTMEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143359-A2 | AMIDO ANTI-VIRAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |