SCHEMBL864945

SCHEMBL864945

Nc1ccc(C#Cc2ccc(N)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 7/20 1.00
MAPT P10636 3/20 0.78
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
ALDH1A1 P00352 5/20 0.47
CYP3A4 P08684 4/20 0.47
TDP1 Q9NUW8 2/20 0.47
TP53 P04637 1/20 0.47
PIK3CA P42336 1/20 0.45
MTOR P42345 1/20 0.45
PDK1 Q15118 1/20 0.45
ALOX15 P16050 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MAPK1 P28482 1/20 0.42
ACHE P22303 1/20 0.42
CA3 P07451 1/20 0.42
THRB P10828 1/20 0.42
CA6 P23280 1/20 0.42
CASP1 P29466 1/20 0.42
HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9611200 1.00 APP (1.00) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL21903463 0.94 APP (0.88) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL1009236 0.88 MAPT (1.00) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL9611197 0.87 APP (0.77) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL8618771 0.86 APP (0.74) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL18763506 0.86 APP (1.00) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL2865734 0.86 APP (0.74) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL8615897 0.86 APP (0.74) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL10035461 0.86 APP (0.74) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL1754885 0.86 APP (0.74) APPMAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119570083-B Toughening type epoxy resin plastic mold and preparation method thereof 南京双星塑料模具有限公司 2025-05-27 CN claimed
CN-120037797-A Azos polymer mixed matrix membrane and preparation method and application thereof 南京工业大学 2025-05-27 CN claimed
CN-120037982-A Tetrazinyl covalent organic framework material, preparation method thereof and application thereof in photocatalytic hydrogen peroxide production 辽宁大学 2025-05-27 CN claimed
CN-119570083-A Toughening type epoxy resin plastic mold and preparation method thereof 南京双星塑料模具有限公司 2025-03-07 CN claimed
CN-114790289-B Preparation method of high-temperature-resistant polyimide resin 中国船舶重工集团公司第七一八研究所 2023-08-11 CN claimed
CN-114790289-A Preparation method of high-temperature-resistant polyimide resin 中国船舶重工集团公司第七一八研究所 2022-07-26 CN claimed
CN-120037797-B Azos polymer mixed matrix membrane and preparation method and application thereof 南京工业大学 2026-05-19 CN disclosed
US-20250214964-A1 COMPOUNDS DERIVED FROM 4-AMINO-N-(4-AMINOPHENYL) BENZAMIDE AND ANALOGUES AND USE THEREOF CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) 2025-07-03 US disclosed
WO-2025127092-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2025-06-19 WO disclosed
WO-2025121189-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2025-06-12 WO disclosed
WO-2025121249-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2025-06-12 WO disclosed
US-20250180952-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-06-05 US disclosed
CN-120037797-A Azos polymer mixed matrix membrane and preparation method and application thereof 南京工业大学 2025-05-27 CN disclosed
EP-0188675-B1 ULTRATHIN POLYMERIC IMINE FILMS AND PROCESS FOR MAKING THE SAME Research Development Corporation of Japan (JP) 1991-06-05 EP disclosed
EP-0409069-A2 Mesogenic polycyanates and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-01-23 EP disclosed
US-4966743-A Process for making ultrathin polymeric imine films RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) 1990-10-30 US disclosed
US-4778720-A PRODUCT OF DIAMINE AND DIIMINE SCHIFF BASE; SEMICONDUCTORS RESEARCH DEV. CORP. OF JAPAN (JP) 1988-10-18 US disclosed
US-4681799-A Ultrathin polymeric imine films and process for making the same RESEARCH DEVELOPMENT CORP. OF JAPAN (JP) 1987-07-21 US disclosed
EP-0188675-A1 Ultrathin polymeric imine films and process for making the same Research Development Corporation of Japan (JP) 1986-07-30 EP disclosed
US-4504559-A Disazo compounds and photoconductive composition as well as electrophotographic light sensitive element containing the same FUJI PHOTO FILM CO., LTD. (JP) 1985-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214964-A1 COMPOUNDS DERIVED FROM 4-AMINO-N-(4-AMINOPHENYL) BENZAMIDE AND ANALOGUES AND USE THEREOF ABAT, AADAT, AADAC APP 1757/4885MAPT 3378/4885MEN1 3045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.