SCHEMBL9611200

SCHEMBL9611200

Nc1ccc(C#Cc2ccc(C#Cc3ccc(N)cc3)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 7/20 1.00
MAPT P10636 3/20 0.78
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
ALDH1A1 P00352 5/20 0.47
CYP3A4 P08684 4/20 0.47
TDP1 Q9NUW8 2/20 0.47
TP53 P04637 1/20 0.47
PIK3CA P42336 1/20 0.45
MTOR P42345 1/20 0.45
PDK1 Q15118 1/20 0.45
ALOX15 P16050 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MAPK1 P28482 1/20 0.42
ACHE P22303 1/20 0.42
CA3 P07451 1/20 0.42
THRB P10828 1/20 0.42
CA6 P23280 1/20 0.42
CASP1 P29466 1/20 0.42
HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL864945 1.00 APP (1.00) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL21903463 0.94 APP (0.88) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL1009236 0.88 MAPT (1.00) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL9611197 0.87 APP (0.77) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL8618771 0.86 APP (0.74) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL18763506 0.86 APP (1.00) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL2865734 0.86 APP (0.74) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL8615897 0.86 APP (0.74) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL10035461 0.86 APP (0.74) APPMAPTMEN1KMT2AALDH1A1
SCHEMBL1754885 0.86 APP (0.74) APPMAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200332193-A1 LIQUID CRYSTAL ELEMENT USED FOR PHASE CONTROL OF ELECTROMAGNETIC WAVE SIGNAL JNC CORPORATION (JP) 2020-10-22 US disclosed
US-20180163135-A1 LIQUID CRYSTAL POLYMERIZED FILMS USING ALIGNMENT FILM AND POLYMERIZABLE LIQUID CRYSTAL COMPOSTION JNC CORPORATION (JP) 2018-06-14 US disclosed
US-20180163135-A1 LIQUID CRYSTAL POLYMERIZED FILMS USING ALIGNMENT FILM AND POLYMERIZABLE LIQUID CRYSTAL COMPOSTION JNC CORPORATION (JP) 2018-06-14 US disclosed
US-8730435-B2 Liquid crystal display device having retardation film formed of liquid crystalline polyimide having photoreactive group JNC CORPORATION (JP) 2014-05-20 US disclosed
US-8730435-B2 Liquid crystal display device having retardation film formed of liquid crystalline polyimide having photoreactive group JNC CORPORATION (JP) 2014-05-20 US disclosed
US-8263732-B2 Photo-alignment film and liquid crystal display element JNC CORPORATION (JP) 2012-09-11 US disclosed
US-8263732-B2 Photo-alignment film and liquid crystal display element JNC CORPORATION (JP) 2012-09-11 US disclosed
US-20120133871-A1 RETARDATION FILM BASED ON OPTICALLY ALIGNED LIQUID CRYSTALLINE POLYIMIDE AND OPTICAL DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2012-05-31 US disclosed
US-20120133871-A1 RETARDATION FILM BASED ON OPTICALLY ALIGNED LIQUID CRYSTALLINE POLYIMIDE AND OPTICAL DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2012-05-31 US disclosed
US-20120113338-A1 LIQUID CRYSTAL DISPLAY DEVICE HAVING RETARDATION FILM FORMED OF LIQUID CRYSTALLINE POLYIMIDE HAVING PHOTOREACTIVE GROUP JNC PETROCHEMICAL CORPORATION (JP) 2012-05-10 US disclosed
US-20120113338-A1 LIQUID CRYSTAL DISPLAY DEVICE HAVING RETARDATION FILM FORMED OF LIQUID CRYSTALLINE POLYIMIDE HAVING PHOTOREACTIVE GROUP JNC PETROCHEMICAL CORPORATION (JP) 2012-05-10 US disclosed
US-8106142-B2 Polyacetylinic oligomers THE BOEING COMPANY (US) 2012-01-31 US disclosed
US-8106142-B2 Polyacetylinic oligomers THE BOEING COMPANY (US) 2012-01-31 US disclosed
US-20100204485-A1 POLYACETYLINIC OLIGOMERS THE BOEING COMPANY 2010-08-12 US disclosed
US-20100204485-A1 POLYACETYLINIC OLIGOMERS THE BOEING COMPANY 2010-08-12 US disclosed
US-20070232780-A1 PHOTO-ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2007-10-04 US disclosed
US-20070232780-A1 PHOTO-ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204485-A1 POLYACETYLINIC OLIGOMERS AADAC, ACMSD, ECPAS APP 3468/4885MAPT 1019/4885MEN1 4503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.