Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13632171 | 0.93 | GAA (0.41) | F10GAAALDH1A1MAPTMAPK1 | |
| SCHEMBL4505024 | 0.84 | F10 (0.54) | F10F2LMNA | |
| SCHEMBL4492540 | 0.80 | F10 (0.62) | F10F2LMNA | |
| SCHEMBL4506998 | 0.80 | F10 (0.53) | F10F2LMNA | |
| SCHEMBL4496530 | 0.80 | F10 (0.56) | F10LMNA | |
| SCHEMBL4515665 | 0.79 | F10 (0.43) | F10F2LMNA | |
| SCHEMBL4506177 | 0.77 | F10 (0.54) | F10F2LMNA | |
| SCHEMBL13632167 | 0.76 | F10 (0.47) | F10MAPTLMNA | |
| SCHEMBL4492429 | 0.76 | LMNA (0.50) | F10ALDH1A1LMNA | |
| SCHEMBL4504908 | 0.76 | F10 (0.53) | F10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615549-B2 | Substituted pyrrolidinones, their manufacture and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-10 | — | — | US | disclosed |
| US-7615549-B2 | Substituted pyrrolidinones, their manufacture and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-10 | — | — | US | disclosed |