Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807116 | 0.89 | RYR2 (1.00) | RYR2 | |
| Aladorian SCHEMBL29379838 | 0.85 | RYR2 (1.00) | RYR2 | |
| Aladorian SCHEMBL3423110 | 0.85 | RYR2 (1.00) | RYR2 | |
| SCHEMBL12265305 | 0.85 | RYR2 (0.77) | RYR2 | |
| SCHEMBL806617 | 0.85 | RYR2 (1.00) | RYR2 | |
| SCHEMBL4112259 | 0.83 | RYR2 (1.00) | RYR2 | |
| SCHEMBL807121 | 0.83 | RYR2 (0.72) | RYR2 | |
| SCHEMBL13632564 | 0.83 | RYR2 (0.77) | RYR2 | |
| SCHEMBL6867443 | 0.82 | RYR2 (0.83) | RYR2 | |
| SCHEMBL3428995 | 0.81 | RYR2 (0.83) | RYR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090292119-A1 | METHODS FOR SYNTHESIZING BENZOTHIAZEPINE COMPOUNDS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090292119-A1 | METHODS FOR SYNTHESIZING BENZOTHIAZEPINE COMPOUNDS | KCNB2, KCNJ2, KCNJ5 | RYR2 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.