Aladorian

Aladorian

SCHEMBL29379838

COc1ccc2c(c1)CN(C(=O)C(=O)O)CCS2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RYR2 Q92736 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aladorian SCHEMBL3423110 1.00 RYR2 (1.00) RYR2
SCHEMBL6867443 0.91 RYR2 (0.83) RYR2
SCHEMBL3428995 0.91 RYR2 (0.83) RYR2
SCHEMBL8127233 0.90 RYR2 (0.81) RYR2
SCHEMBL4112259 0.90 RYR2 (1.00) RYR2
SCHEMBL12777288 0.90 RYR2 (0.81) RYR2
SCHEMBL807117 0.88 RYR2 (0.79) RYR2
SCHEMBL26344260 0.88 RYR2 (0.78) RYR2
SCHEMBL806687 0.87 RYR2 (1.00) RYR2
SCHEMBL3428542 0.87 RYR2 (0.77) RYR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12485088-B2 Rapidly-orodispersible tablets having an interior cavity Aprecia Pharmaceuticals LLC (US) 2025-12-02 US disclosed
US-20250255882-A1 TREATMENT OF CARDIAC CONDITION RELATED COGNITIVE DYSFUNCTION UNIV COLUMBIA (US) 2025-08-14 US disclosed
US-12324856-B2 Oral drug dosage form comprising drug in the form of nanoparticles Triastek, Inc. (CN) 2025-06-10 US disclosed
EP-4512394-A2 DOSAGE FORMS AND USE THEREOF Triastek, Inc. (CN) 2025-02-26 EP disclosed
US-20240408023-A1 DOSAGE FORMS OF CONTROLLED RELEASE AT SPECIFIC GASTROINTESTINAL SITES Triastek, Inc. (CN) 2024-12-12 US disclosed
EP-4171518-B1 RAPIDLY-ORODISPERSIBLE TABLETS HAVING AN INTERIOR CAVITY Aprecia Pharmaceuticals LLC (US) 2024-12-11 EP disclosed
US-20240342094-A1 COMPARTMENTED PHARMACEUTICAL DOSAGE FORMS Triastek, Inc. (CN) 2024-10-17 US disclosed
EP-3302442-B1 DOSAGE FORMS AND USE THEREOF TRIASTEK INC (CN) 2024-10-16 EP disclosed
US-12102721-B2 Dosage forms of controlled release at specific gastrointestinal sites Triastek, Inc. (CN) 2024-10-01 US disclosed
US-12042562-B2 3D printing methods for compartmented pharmaceutical dosage forms Triastek, Inc. (CN) 2024-07-23 US disclosed
CN-116018131-A Fast orodispersible tablet with inner cavity 阿普雷奇亚制药有限责任公司 2023-04-25 CN disclosed
US-11548928-B2 Engineered platelets for targeted delivery of a therapeutic agent JPV01 LTD. (GB) 2023-01-10 US disclosed
US-11518796-B2 Engineered platelets for targeted delivery of a therapeutic agent JPV01 LTD. (GB) 2022-12-06 US disclosed
US-11433022-B2 Rapidly-orodispersible tablets having an in interior cavity Aprecia Pharmaceuticals LLC (US) 2022-09-06 US disclosed
US-20220251165-A1 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 LTD. (GB) 2022-08-11 US disclosed
EP-4026898-A1 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 Ltd (GB) 2022-07-13 EP disclosed
EP-3981392-A1 CONTROLLED RELEASE DOSAGE FORM Triastek, Inc. (CN) 2022-04-13 EP disclosed
US-11278499-B2 Oral drug dosage form comprising various release profiles Triastek, Inc. (CN) 2022-03-22 US disclosed
US-20220054409-A1 RAPIDLY-ORODISPERSIBLE TABLETS HAVING AN INTERIOR CAVITY Aprecia Pharmaceuticals LLC 2022-02-24 US disclosed
US-20220041684-A1 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 LTD. (GB) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12324856-B2 Oral drug dosage form comprising drug in the form of nanoparticles CYP2D6, CYP3A5, CYP3A7 RYR2 3907/4885
US-11278499-B2 Oral drug dosage form comprising various release profiles CYP2D6, CYP3A7, CYP3A5 RYR2 2022/4885
US-20240342094-A1 COMPARTMENTED PHARMACEUTICAL DOSAGE FORMS CYP2D6, CYP3A5, CYP2F1 RYR2 3759/4885
US-12042562-B2 3D printing methods for compartmented pharmaceutical dosage forms CYP3A43, HTR3D, CYP3A7 RYR2 4049/4885
US-20250255882-A1 TREATMENT OF CARDIAC CONDITION RELATED COGNITIVE DYSFUNCTION CACNA1F, CACNA1S, RYR2 RYR2 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.