Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425724 | 0.91 | RYR2 (0.80) | RYR2 | |
| Aladorian SCHEMBL3423110 | 0.91 | RYR2 (1.00) | RYR2 | |
| Aladorian SCHEMBL29379838 | 0.91 | RYR2 (1.00) | RYR2 | |
| SCHEMBL807117 | 0.89 | RYR2 (0.79) | RYR2 | |
| SCHEMBL3430812 | 0.89 | RYR2 (0.67) | RYR2 | |
| SCHEMBL806687 | 0.88 | RYR2 (1.00) | RYR2 | |
| SCHEMBL3428542 | 0.88 | RYR2 (0.77) | RYR2 | |
| SCHEMBL13406749 | 0.87 | RYR2 (0.64) | RYR2 | |
| SCHEMBL12265307 | 0.87 | RYR2 (0.88) | RYR2 | |
| SCHEMBL6867475 | 0.87 | RYR2 (0.86) | RYR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250159-A1 | PROCESS FOR PREPARING BENZOTHIAZEPINES FROM GAMMA-AMINOALKYLBENZENES | Armgo Pharma, Inc. (US) | 2010-11-17 | — | — | EP | disclosed |
| US-7704990-B2 | Agents for preventing and treating disorders involving modulation of the RyR receptors | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-04-27 | — | — | US | disclosed |
| WO-2009111463-A1 | PROCESS FOR PREPARING BENZOTHIAZEPINES FROM GAMMA-AMINOALKYLBENZENES | ARMGO PHARMA, INC. (US) | 2009-09-11 | — | — | WO | disclosed |