Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4984200 | 1.00 | HPGD (0.53) | HPGDKMT2ANPSR1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL6261119 | 0.98 | GAA (0.51) | HPGDKMT2ANPSR1KDM4EMAPT | |
| SCHEMBL5007669 | 0.98 | DPP4 (0.54) | HPGDKMT2ANPSR1KDM4EMAPT | |
| SCHEMBL14027830 | 0.98 | DPP4 (0.54) | HPGDKMT2ANPSR1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL4741021 | 0.96 | DPP4 (0.52) | HPGDKMT2ANPSR1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL4741023 | 0.96 | DPP4 (0.52) | HPGDKMT2ANPSR1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL21995057 | 0.89 | ROCK2 (0.54) | KMT2AKDM4EDPP4ROCK2CYP3A4 | |
| Hydrochloric Acid SCHEMBL21995059 | 0.89 | ROCK2 (0.54) | KMT2AKDM4EDPP4ROCK2CYP3A4 | |
| SCHEMBL4702239 | 0.83 | ALDH1A1 (0.63) | HPGDKMT2AKDM4EGAATSHR | |
| SCHEMBL22642320 | 0.83 | ROCK2 (0.50) | KMT2AKDM4EMAPTDPP4ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903353-B1 | Imidazolidine derivates, their preparation and use, and pharmaceutical compositions containing them | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-11-25 | — | — | EP | disclosed |