Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 4/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638393 | 0.88 | SCD (0.56) | SCDPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL4513108 | 0.85 | SCD (0.68) | SCDPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL13638395 | 0.76 | SCD (0.74) | SCD | |
| SCHEMBL21637791 | 0.65 | SCD (0.46) | SCDRAB9AMEN1NPC1KMT2A | |
| SCHEMBL15692576 | 0.64 | ACHE (0.50) | RAB9AKMT2A | |
| SCHEMBL27666027 | 0.64 | CHRM1 (0.36) | RAB9AMEN1NPC1KMT2AMAPT | |
| SCHEMBL4403095 | 0.64 | PDPK1 (0.47) | RAB9ANPC1MAPT | |
| SCHEMBL27850987 | 0.63 | ACHE (0.47) | RAB9AMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL27666508 | 0.63 | HTR2A (0.50) | MEN1NPC1KMT2AMAPTHTR1A | |
| SCHEMBL14870434 | 0.63 | SCD (0.60) | SCDRAB9ANPC1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130012709-A1 | NOVEL INHIBITORS OF STEAROYL-CoA-DESATURASE-1 AND THEIR USES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-01-10 | — | — | US | disclosed |
| US-20090291955-A1 | Azacyclohexane Derivatives as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase | MERCK FROSST CANADA LTD. (CA) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291955-A1 | Azacyclohexane Derivatives as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase | SCD, SCD5, SREBF1 | SCD 1/4885PIK3CD 1385/4885PIK3CA 1776/4885 |
| US-20130012709-A1 | NOVEL INHIBITORS OF STEAROYL-CoA-DESATURASE-1 AND THEIR USES | SCD, SCD5, FADS2 | SCD 1/4885PIK3CD 4022/4885PIK3CA 4193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.