SCHEMBL13633570

SCHEMBL13633570

Cn1c2ccccc2c(=O)c2ccc(/C=C/c3ccc4[nH]cnc4c3)cc21

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.46
IP6K1 Q92551 5/20 0.43
IP6K3 Q96PC2 2/20 0.43
IP6K2 Q9UHH9 1/20 0.43
NPC1 O15118 5/20 0.42
RAB9A P51151 5/20 0.42
POLB P06746 3/20 0.42
RXFP1 Q9HBX9 2/20 0.42
PTPN7 P35236 1/20 0.42
DUSP3 P51452 1/20 0.42
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 6/20 0.40
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
TLR9 Q9NR96 1/20 0.40
HCRTR1 O43613 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13633572 0.75 ATM (0.55) ATMNPC1RAB9APOLBRXFP1
SCHEMBL13633603 0.75 ATM (0.55) ATMNPC1RAB9APOLBRXFP1
SCHEMBL10817399 0.73 IP6K1 (0.59) IP6K1IP6K3IP6K2NPC1RAB9A
SCHEMBL13633641 0.71 ATM (0.50) ATMNPC1RAB9APOLBRXFP1
SCHEMBL12419784 0.71 GPR3 (0.57) ATMNPC1RAB9APOLBL3MBTL1
SCHEMBL85776 0.71 ATM (0.71) ATMNPC1RAB9APOLBRXFP1
SCHEMBL29361718 0.71 ATM (0.71) ATMNPC1RAB9APOLBRXFP1
SCHEMBL13633642 0.69 ATM (0.50) ATMNPC1RAB9APOLBL3MBTL1
SCHEMBL13480892 0.69 GPR3 (0.53) ATMNPC1RAB9APOLBRXFP1
SCHEMBL13633571 0.68 ATM (0.63) ATMNPC1RAB9APOLBRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7611909-B1 Acridinium compound for use in the concurrent detection of target analytes in immunoassays or nucleic acid assays SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2009-11-03 US disclosed
US-7611909-B1 Acridinium compound for use in the concurrent detection of target analytes in immunoassays or nucleic acid assays SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2009-11-03 US disclosed