SCHEMBL12419784

SCHEMBL12419784

Cn1c2ccccc2c2cc3c(cc21)c1ccc(/C=C/c2ccc4c5cc6c(cc5n(C)c4c2)c2ccccc2n6C)cc1n3C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.57
KIF11 P52732 1/20 0.51
MAPT P10636 5/20 0.49
KDM4E B2RXH2 4/20 0.49
HPGD P15428 4/20 0.49
ALDH1A1 P00352 3/20 0.49
HSD17B10 Q99714 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
HTT P42858 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
LMNA P02545 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
PABPC1 P11940 1/20 0.47
ATM Q13315 1/20 0.46
PSEN1 P49768 1/20 0.44
PSEN2 P49810 1/20 0.44
APH1B Q8WW43 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12419783 0.93 GPR3 (0.57) GPR3KIF11MAPTKDM4EHPGD
SCHEMBL13480892 0.90 GPR3 (0.53) GPR3KIF11MAPTKDM4EHPGD
SCHEMBL14366792 0.89 GPR3 (0.61) GPR3MAPTKDM4EHPGDALDH1A1
SCHEMBL13451224 0.86 GPR3 (0.53) GPR3KIF11MAPTKDM4EHPGD
SCHEMBL3423941 0.84 GPR3 (0.80) GPR3KIF11MAPTKDM4EHPGD
SCHEMBL28217032 0.84 GPR3 (0.55) GPR3MAPTKDM4EHPGDALDH1A1
SCHEMBL17853291 0.83 KIF11 (0.50) GPR3KIF11MAPTKDM4EHPGD
SCHEMBL13480890 0.83 KDM4E (0.50) GPR3KIF11MAPTKDM4EHPGD
SCHEMBL15576935 0.83 PSEN1 (0.51) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL11350562 0.82 GPR3 (0.57) GPR3KIF11MAPTKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8003807-B2 organic thin film transistor with a semiconductor layer including the small molecule having didodecylindolo[3,2-b]carbazole groups XEROX CORPORATION (US) 2011-08-23 US disclosed
US-7868186-B2 Device containing polymer having indolocarbazole- repeat unit and divalent linkage XEROX CORPORATION (US) 2011-01-11 US disclosed
US-7829727-B2 Device containing compound having indolocarbazole moiety and divalent linkage XEROX CORPORATION (US) 2010-11-09 US disclosed
US-20100230670-A1 DEVICE CONTAINING COMPOUND HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE XEROX CORPORATION (US) 2010-09-16 US disclosed
US-20090114909-A1 organic thin film transistor with a semiconductor layer including the polymer of 2,8-Bis(2-thienyl)-5,11-didodecylindolo[3,2-b]carbazole; organic photovoltaics XEROX CORPORATION (US) 2009-05-07 US disclosed
US-7528261-B2 Small molecule compound having indolocarbazole moiety and divalent linkage XEROX CORPORATION (US) 2009-05-05 US disclosed
US-20080207917-A1 POLYMER HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE XEROX CORPORATION (US) 2008-08-28 US disclosed
US-7396852-B2 Compound having indolocarbazole moiety and divalent linkage XEROX CORPORATION (US) 2008-07-08 US disclosed
US-20080103314-A1 SMALL MOLECULE COMPOUND HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE XEROX CORPORATION (US) 2008-05-01 US disclosed
US-20070112167-A1 Device containing compound having indolocarbazole moiety and divalent linkage XEROX CORPORATION 2007-05-17 US disclosed
US-20070112172-A1 Compound having indolocarbazole moiety and divalent linkage XEROX CORPORATION 2007-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070112172-A1 Compound having indolocarbazole moiety and divalent linkage INMT, IDO2, GRIN2C GPR3 1336/4885KIF11 2271/4885MAPT 163/4885
US-20080103314-A1 SMALL MOLECULE COMPOUND HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE SLC43A1, SLC7A5, KCNN2 GPR3 1530/4885KIF11 2030/4885MAPT 153/4885
US-20100230670-A1 DEVICE CONTAINING COMPOUND HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE BRD4, BICRA, INMT GPR3 2016/4885KIF11 1986/4885MAPT 955/4885
US-20080207917-A1 POLYMER HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE SGTA, MTCL3, SMC3 GPR3 2775/4885KIF11 1412/4885MAPT 196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.