Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192241 | 1.00 | DHODH (0.45) | DHODHNPC1RAB9AKDM4EPKM | |
| SCHEMBL4183514 | 0.95 | NPC1 (0.44) | DHODHNPC1RAB9AKDM4EPKM | |
| SCHEMBL4480370 | 0.93 | MEN1 (0.42) | MAOBMEN1KMT2AGSK3BBACE1 | |
| SCHEMBL13633574 | 0.92 | DHODH (0.39) | DHODHNPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL3034156 | 0.90 | PLA2G2A (0.48) | DHODHNPC1KDM4EATML3MBTL1 | |
| SCHEMBL4190377 | 0.88 | MEN1 (0.42) | MAOBMEN1KMT2ATOP2ATOP2B | |
| SCHEMBL4183628 | 0.88 | MAPT (0.39) | DHODHNPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL924047 | 0.87 | PLA2G2A (0.51) | DHODHNPC1RAB9AKDM4EATM | |
| SCHEMBL13633650 | 0.87 | MAPT (0.38) | DHODHNPC1RAB9AKDM4EKMT2A | |
| SCHEMBL7532967 | 0.87 | TACR3 (0.47) | DHODHNPC1ATML3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611909-B1 | Acridinium compound for use in the concurrent detection of target analytes in immunoassays or nucleic acid assays | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2009-11-03 | — | — | US | disclosed |