Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
| ▸ | TOP2A | P11388 | 2/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13633574 | 0.95 | DHODH (0.39) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL4183514 | 0.92 | NPC1 (0.44) | KDM4EDHODHTOP2ATOP2BKMT2A | |
| SCHEMBL4190377 | 0.92 | MEN1 (0.42) | TOP2ATOP2BAPPHDAC1HDAC2 | |
| SCHEMBL4339220 | 0.90 | MAPT (0.39) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL9631380 | 0.88 | TDP1 (0.47) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL4480370 | 0.87 | MEN1 (0.42) | APPHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL13633577 | 0.87 | DHODH (0.45) | KDM4EDHODHTOP2ATOP2BKMT2A | |
| SCHEMBL4192241 | 0.87 | DHODH (0.45) | KDM4EDHODHTOP2ATOP2BKMT2A | |
| SCHEMBL7533840 | 0.85 | TDP1 (0.42) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL4183628 | 0.84 | MAPT (0.39) | MAPTKDM4ELMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611909-B1 | Acridinium compound for use in the concurrent detection of target analytes in immunoassays or nucleic acid assays | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2009-11-03 | — | — | US | disclosed |