Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TOP2A | P11388 | 3/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533840 | 0.95 | TDP1 (0.42) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL5663425 | 0.94 | LMNA (0.44) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL7532967 | 0.91 | TACR3 (0.47) | TDP1KMT2ATOP2ATOP2BL3MBTL1 | |
| SCHEMBL3034156 | 0.91 | PLA2G2A (0.48) | TDP1KMT2ALMNAMAPTTOP2A | |
| SCHEMBL4183628 | 0.90 | MAPT (0.39) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL4339220 | 0.90 | MAPT (0.39) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL7533851 | 0.90 | MAPT (0.40) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL15413120 | 0.89 | KMT2A (0.48) | KMT2ALMNAMAPTTOP2AALDH1A1 | |
| SCHEMBL13223627 | 0.89 | TOP2A (0.50) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL13633574 | 0.88 | DHODH (0.39) | TDP1KMT2ASLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263657-B1 | POLYSUBSTITUTED ARYL ACRIDINIUM ESTERS | Ciba Corning Diagnostics Corp. (US) | 1992-05-13 | — | — | EP | disclosed |
| US-5110932-A | Chemiluminescent immunoassay | CIBA CORNING DIAGNOSTICS CORP. (US) | 1992-05-05 | — | — | US | disclosed |
| US-4918192-A | LUMINESCENCE; LABELS FOR IMMUNOASSAY | CIBA CORNING DIAGNOSTICS CORP. (US) | 1990-04-17 | — | — | US | disclosed |
| US-4745181-A | STABLE LABELS FOR CHEMILUMINESCENT IMMUNOASSAY | CIBA CORNING DIAGNOSTICS CORP. (US) | 1988-05-17 | — | — | US | disclosed |