Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12972248 | 0.91 | ACE (0.51) | LCKALOX15ALOX12ALDH1A1KDM4E | |
| SCHEMBL15976477 | 0.84 | LCK (0.71) | LCKXDHMDM4MDM2MMP1 | |
| Hydrochloric Acid SCHEMBL4717659 | 0.82 | LCK (0.62) | LCKXDHMDM4MDM2MMP1 | |
| SCHEMBL6267583 | 0.80 | LCK (0.70) | LCKXDHMDM4MDM2MMP1 | |
| SCHEMBL11864242 | 0.79 | LCK (0.68) | LCKXDHMDM4MDM2MMP1 | |
| SCHEMBL2947377 | 0.79 | LCK (0.61) | LCKMDM4MDM2ALOX15ALDH1A1 | |
| SCHEMBL15976476 | 0.79 | LCK (0.71) | LCKXDHMDM4MDM2MMP1 | |
| SCHEMBL10792628 | 0.79 | LCK (0.71) | LCKXDHMDM4MDM2MMP1 | |
| SCHEMBL10792638 | 0.79 | LCK (0.71) | LCKXDHMDM4MDM2MMP1 | |
| SCHEMBL3013717 | 0.78 | LCK (0.64) | LCKXDHKLK5ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815793-B2 | Polymeric compositions and related methods of use | NORTHWESTERN UNIVERSITY (US) | 2014-08-26 | — | — | US | disclosed |
| US-7618937-B2 | Peptidomimetic polymers for antifouling surfaces | NORTHWESTERN UNIVERSITY (US) | 2009-11-17 | — | — | US | disclosed |