Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.68 |
| ▸ | XDH | P47989 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11854802 | 0.89 | LCK (0.55) | LCKALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL6267583 | 0.87 | LCK (0.70) | LCKXDHNPSR1ALDH1A1LNPEP | |
| SCHEMBL10099849 | 0.87 | LCK (0.62) | LCKNPSR1ALDH1A1HDAC1HDAC6 | |
| SCHEMBL10792628 | 0.86 | LCK (0.71) | LCKXDHALDH1A1LNPEPMDM4 | |
| SCHEMBL10792638 | 0.86 | LCK (0.71) | LCKXDHALDH1A1LNPEPMDM4 | |
| SCHEMBL15976477 | 0.86 | LCK (0.71) | LCKXDHNPSR1ALDH1A1LNPEP | |
| SCHEMBL15976476 | 0.86 | LCK (0.71) | LCKXDHALDH1A1LNPEPMDM4 | |
| SCHEMBL6139811 | 0.85 | LCK (0.67) | LCKNPSR1ALDH1A1HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL4717659 | 0.84 | LCK (0.62) | LCKXDHNPSR1ALDH1A1LNPEP | |
| SCHEMBL11539388 | 0.84 | LCK (0.65) | LCKXDHNPSR1ALDH1A1LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939253-A | Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease | INTERX RESEARCH CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |