Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.70 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.52 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 2/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11864242 | 0.87 | LCK (0.68) | LCKXDHMDM4MDM2MMP1 | |
| SCHEMBL15976476 | 0.87 | LCK (0.71) | LCKXDHMDM4MDM2MMP1 | |
| SCHEMBL10792638 | 0.87 | LCK (0.71) | LCKXDHMDM4MDM2MMP1 | |
| SCHEMBL15976477 | 0.87 | LCK (0.71) | LCKXDHMDM4MDM2MMP1 | |
| SCHEMBL10792628 | 0.87 | LCK (0.71) | LCKXDHMDM4MDM2MMP1 | |
| SCHEMBL6139811 | 0.86 | LCK (0.67) | LCKHDAC1HDAC6ALDH1A1NPSR1 | |
| SCHEMBL8008620 | 0.84 | LCK (0.67) | LCKERCC1ERCC4XDHMDM4 | |
| SCHEMBL5310702 | 0.84 | LCK (0.67) | LCKERCC1ERCC4XDHMDM4 | |
| SCHEMBL6140530 | 0.83 | LCK (0.67) | LCKXDHMMP1MMP2MMP3 | |
| SCHEMBL10099849 | 0.83 | LCK (0.62) | LCKHDAC1HDAC6ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005072723-A1 | PHARMACEUTICAL COMPOSITION COMPRISING HYDROXYLPHENYL DERIVATIVES OF ROSMARINIC ACID FOR ANTICANCER | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2005-08-11 | — | — | WO | claimed |
| US-20040082664-A1 | Derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2004-04-29 | — | — | US | claimed |
| WO-2005072723-A1 | PHARMACEUTICAL COMPOSITION COMPRISING HYDROXYLPHENYL DERIVATIVES OF ROSMARINIC ACID FOR ANTICANCER | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2005-08-11 | — | — | WO | disclosed |
| US-20040082664-A1 | Derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082664-A1 | Derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition | LCK, SRC, FYN | LCK 1/4885ERCC1 4794/4885ERCC4 4778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.