Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.32 |
| ▸ | ATM | Q13315 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638572 | 0.94 | P2RY12 (0.37) | P2RY12ATM | |
| SCHEMBL13633779 | 0.88 | P2RY12 (0.36) | P2RY12PTGER3 | |
| SCHEMBL13633639 | 0.87 | SMN1; SMN2 (0.36) | P2RY12 | |
| SCHEMBL14200753 | 0.86 | MAPT (0.39) | P2RY12PTGER3ATM | |
| SCHEMBL12161540 | 0.84 | P2RY12 (0.40) | P2RY12PTGER3 | |
| SCHEMBL13638573 | 0.81 | P2RY12 (0.43) | P2RY12PTGER3 | |
| SCHEMBL12161536 | 0.81 | P2RY12 (0.43) | P2RY12PTGER3 | |
| SCHEMBL14228353 | 0.80 | P2RY12 (0.42) | P2RY12PTGER3 | |
| SCHEMBL12161526 | 0.80 | P2RY12 (0.42) | P2RY12PTGER3 | |
| SCHEMBL9922974 | 0.79 | MAPT (0.39) | P2RY12ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |