SCHEMBL13634109

SCHEMBL13634109

CCCCn1c2ccccc2c2cc(N(c3ccccc3)c3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3ccccc3-4)ccc21

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 10/20 0.43
PGR P06401 5/20 0.41
RORA P35398 5/20 0.41
RORC P51449 5/20 0.41
RORB Q92753 5/20 0.41
ALDH1A1 P00352 2/20 0.40
HPGD P15428 1/20 0.40
NPC1 O15118 2/20 0.38
CNR1 P21554 1/20 0.38
KDM4E B2RXH2 1/20 0.37
PABPC1 P11940 1/20 0.37
PKM P14618 1/20 0.37
RAB9A P51151 1/20 0.37
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13634132 0.94 ALDH1A1 (0.46) CNR2PGRRORCALDH1A1HPGD
SCHEMBL13634124 0.89 MAPT (0.45) RORCALDH1A1HPGDKDM4EPKM
SCHEMBL12560196 0.87 KDM4E (0.40) ALDH1A1HPGDKDM4EPABPC1
SCHEMBL25563154 0.87 KDM4E (0.40) ALDH1A1HPGDKDM4EPABPC1
SCHEMBL24022276 0.85 MAPT (0.48) RORCALDH1A1HPGDKDM4EPKM
SCHEMBL13634070 0.85 KDM4E (0.46) RORCALDH1A1HPGDKDM4E
SCHEMBL13638733 0.85 CNR2 (0.31) CNR2
SCHEMBL18810187 0.85 CNR2 (0.31) CNR2
SCHEMBL25563549 0.84 KDM4E (0.38) ALDH1A1HPGDKDM4EPABPC1
SCHEMBL25563620 0.84 KDM4E (0.38) ALDH1A1HPGDKDM4EPABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180175295-A1 SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2018-06-21 US disclosed
US-9548457-B2 Spirofluorene derivative, material for light-emitting element, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORIES CO., LTD. (JP) 2017-01-17 US disclosed
US-9548457-B2 Spirofluorene derivative, material for light-emitting element, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORIES CO., LTD. (JP) 2017-01-17 US disclosed
US-20160087209-A1 SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2016-03-24 US disclosed
US-20160087209-A1 SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2016-03-24 US disclosed
US-8304094-B2 High light efficincy; hole transporting substance; phosphorescence SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-11-06 US disclosed
US-8304094-B2 High light efficincy; hole transporting substance; phosphorescence SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-11-06 US disclosed
WO-2008105349-A1 LIGHT-EMITTING ELEMENT USING SPIROFLUORENE DERIVATIVE AND ELECTRONIC APPLIANCE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-09-04 WO disclosed
US-20080206598-A1 Light-emitting element using spirofluorene derivative and electronic appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-08-28 US disclosed
US-20080206598-A1 Light-emitting element using spirofluorene derivative and electronic appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180175295-A1 SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE GRK1, PTGER2, PTGER1 CNR2 2838/4885PGR 607/4885RORA 247/4885
US-20160087209-A1 SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE GRK1, PTGER2, PTGER1 CNR2 2838/4885PGR 607/4885RORA 247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.