SCHEMBL13634116

SCHEMBL13634116

CCCCCCCCCCCCCCCCCCCCCCC(O)C(=O)OCCCCCC

nearest known ligand 0.75

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 6/20 0.59
NAAA Q02083 1/20 0.59
FFAR1 O14842 1/20 0.59
EPHX1 P07099 1/20 0.50
TSHR P16473 2/20 0.48
ZDHHC7 Q9NXF8 1/20 0.47
MAPT P10636 1/20 0.47
HCAR2 Q8TDS4 1/20 0.46
RAD52 P43351 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL151961 1.00 GPR84 (0.59) GPR84NAAAFFAR1EPHX1TSHR
SCHEMBL4133210 1.00 GPR84 (0.59) GPR84NAAAFFAR1EPHX1TSHR
SCHEMBL8376969 1.00 GPR84 (0.59) GPR84NAAAFFAR1EPHX1TSHR
SCHEMBL11922960 1.00 GPR84 (0.59) GPR84NAAAFFAR1EPHX1TSHR
SCHEMBL6864319 1.00 GPR84 (0.59) GPR84NAAAFFAR1EPHX1TSHR
SCHEMBL8375622 1.00 GPR84 (0.59) GPR84NAAAFFAR1EPHX1TSHR
SCHEMBL17373195 1.00 GPR84 (0.59) GPR84NAAAFFAR1EPHX1TSHR
SCHEMBL13002969 1.00 GPR84 (0.59) GPR84NAAAFFAR1EPHX1TSHR
SCHEMBL8981942 1.00 GPR84 (0.59) GPR84NAAAFFAR1EPHX1TSHR
SCHEMBL15129028 1.00 GPR84 (0.59) GPR84NAAAFFAR1EPHX1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8653117-B2 Composition comprising at least one oxazoline to inhibit migration of langerhans cells, and uses thereof LABORATOIRES EXPANSCIENCE (FR) 2014-02-18 US disclosed
US-8653117-B2 Composition comprising at least one oxazoline to inhibit migration of langerhans cells, and uses thereof LABORATOIRES EXPANSCIENCE (FR) 2014-02-18 US disclosed
US-8304453-B2 Composition comprising at least one alkanolamide to inhibit migration of langerhans cells and uses therof LABORATOIRES EXPANSCIENCE (FR) 2012-11-06 US disclosed
US-8304453-B2 Composition comprising at least one alkanolamide to inhibit migration of langerhans cells and uses therof LABORATOIRES EXPANSCIENCE (FR) 2012-11-06 US disclosed
US-20090137453-A1 COMPOSITION COMPRISING AT LEAST ONE OXAZOLINE TO INHIBIT MIGRATION OF LANGERHANS CELLS, AND USES THEREOF MSIKA PHILIPPE 2009-05-28 US disclosed
US-20090137453-A1 COMPOSITION COMPRISING AT LEAST ONE OXAZOLINE TO INHIBIT MIGRATION OF LANGERHANS CELLS, AND USES THEREOF MSIKA PHILIPPE 2009-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137453-A1 COMPOSITION COMPRISING AT LEAST ONE OXAZOLINE TO INHIBIT MIGRATION OF LANGERHANS CELLS, AND USES THEREOF ARG1, MIF, ZAP70 GPR84 654/4885NAAA 961/4885FFAR1 1409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.