Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774659 | 0.95 | ALDH1A1 (0.59) | KDM4ETSHRALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL2769406 | 0.94 | ALDH1A1 (0.58) | KDM4ETSHRALDH1A1GAAMAPT | |
| SCHEMBL495753 | 0.88 | KDM4E (0.62) | KDM4ETSHRALDH1A1GAAMAPT | |
| SCHEMBL13162651 | 0.87 | SMN1; SMN2 (0.51) | KDM4ETSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13638974 | 0.85 | SMN1; SMN2 (0.54) | KDM4ETSHRALDH1A1GAAMAPT | |
| SCHEMBL13163094 | 0.85 | ALDH1A1 (0.50) | KDM4ETSHRALDH1A1MAPTHPGD | |
| SCHEMBL146852 | 0.83 | TSHR (0.55) | KDM4ETSHRALDH1A1MAPTHSD17B10 | |
| SCHEMBL13162553 | 0.83 | ALDH1A1 (0.57) | KDM4ETSHRALDH1A1GAAMAPT | |
| SCHEMBL13161883 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2MAPK1HCRTR1 | |
| SCHEMBL13161998 | 0.82 | SMN1; SMN2 (0.55) | KDM4ETSHRALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |