Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774659 | 0.90 | ALDH1A1 (0.59) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A | |
| Hydrochloric Acid SCHEMBL2769406 | 0.89 | ALDH1A1 (0.58) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A | |
| SCHEMBL589672 | 0.87 | KDM4E (0.61) | SMN1; SMN2KMT2AALDH1A1KDM4EGLA | |
| SCHEMBL5058405 | 0.86 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A | |
| SCHEMBL13634159 | 0.85 | KDM4E (0.54) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A | |
| Hydrochloric Acid SCHEMBL5054616 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A | |
| SCHEMBL1013959 | 0.85 | HTT (0.59) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A | |
| SCHEMBL30230313 | 0.85 | HTT (0.62) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A | |
| SCHEMBL3590235 | 0.84 | PARP1 (0.49) | HTTALDH1A1KDM4EHPGDAOC3 | |
| SCHEMBL12858369 | 0.84 | HCRTR1 (0.55) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |