Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145235 | 0.87 | PARP1 (0.49) | NOS1NOS3NOS2NCF1HRH3 | |
| Hydrochloric Acid SCHEMBL347360 | 0.86 | PARP1 (0.48) | NOS1NOS3NOS2NCF1HRH3 | |
| SCHEMBL145531 | 0.86 | ALDH1A1 (0.54) | NOS1NCF1HRH3AOC3ALDH1A1 | |
| SCHEMBL2774659 | 0.85 | ALDH1A1 (0.59) | AOC3ALDH1A1HIF1AEPAS1HTT | |
| Lithium Ion SCHEMBL145530 | 0.85 | KCNJ1 (0.48) | NOS1NOS3NOS2NCF1HRH3 | |
| SCHEMBL13634492 | 0.84 | SMN1; SMN2 (0.50) | NOS1NOS3NOS2HRH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2769406 | 0.84 | ALDH1A1 (0.58) | AOC3ALDH1A1HIF1AEPAS1HTT | |
| SCHEMBL6708339 | 0.83 | NPC1 (0.57) | NOS1NOS3NOS2HRH3ALDH1A1 | |
| SCHEMBL146852 | 0.83 | TSHR (0.55) | ALDH1A1HTTSMN1; SMN2LMNAMAPT | |
| SCHEMBL13163094 | 0.83 | ALDH1A1 (0.50) | NCF1HRH3AOC3ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |