SCHEMBL145235

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL347360	0.99	PARP1 (0.48)	PARP1PARP2PARP3NCF1HRH3
	SCHEMBL3590235	0.89	PARP1 (0.49)	PARP1PARP2PARP3NCF1HRH3
	SCHEMBL13634176	0.87	NOS1 (0.50)	NCF1HRH3NOS1AOC3NOS3
	SCHEMBL145531	0.87	ALDH1A1 (0.54)	NCF1HRH3NOS1AOC3HPGD
	Lithium Ion SCHEMBL145530	0.86	KCNJ1 (0.48)	NCF1HRH3NOS1AOC3NOS3
	SCHEMBL377882	0.86	SIGMAR1 (0.54)	PARP1PARP2PARP3AOC3ALDH1A1
	SCHEMBL3641139	0.84	PARP1 (0.51)	PARP1PARP2PARP3NCF1HRH3
	SCHEMBL13162039	0.84	CHUK (0.53)	PARP1PARP2PARP3NCF1HRH3
	SCHEMBL2774659	0.84	ALDH1A1 (0.59)	AOC3HPGDALDH1A1LMNAMAPT
	SCHEMBL13163094	0.84	ALDH1A1 (0.50)	NCF1HRH3AOC3HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.