Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RORA | P35398 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 4/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12462123 | 0.95 | KDM4E (0.42) | KDM4EATML3MBTL1RORARORC | |
| SCHEMBL23372135 | 0.87 | RORA (0.54) | KDM4EATML3MBTL1RORARORC | |
| SCHEMBL3787566 | 0.84 | KDM4E (0.48) | KDM4EATML3MBTL1HDAC4AKR1C4 | |
| SCHEMBL1201083 | 0.84 | KDM4E (0.48) | KDM4EATML3MBTL1HDAC4AKR1C4 | |
| SCHEMBL13776939 | 0.84 | RORA (0.47) | KDM4EATML3MBTL1RORARORC | |
| SCHEMBL13932547 | 0.84 | RORA (0.47) | KDM4EATML3MBTL1RORARORC | |
| SCHEMBL13776934 | 0.84 | KDM4E (0.42) | KDM4EATML3MBTL1RORARORC | |
| SCHEMBL10067556 | 0.84 | RORA (0.47) | KDM4EATML3MBTL1RORARORC | |
| SCHEMBL13385104 | 0.82 | RORA (0.41) | KDM4EATML3MBTL1RORARORC | |
| SCHEMBL25919857 | 0.82 | RORA (0.45) | KDM4EATML3MBTL1RORARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116531-A1 | CBP COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2009-11-11 | — | — | EP | disclosed |