SCHEMBL3787566

SCHEMBL3787566

OCc1ccc2c(c1)c1ccccc1n2-c1ccc(-c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.48
ATM Q13315 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
PGR P06401 1/20 0.44
HDAC4 P56524 1/20 0.43
AKR1C4 P17516 1/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41
PTPN1 P18031 2/20 0.41
POLB P06746 2/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
BAZ2B Q9UIF8 1/20 0.38
BAZ2A Q9UIF9 1/20 0.38
F2 P00734 1/20 0.37
F10 P00742 1/20 0.37
PRSS1 P07477 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1201083 1.00 KDM4E (0.48) KDM4EATML3MBTL1PGRHDAC4
SCHEMBL31419534 0.87 KDM4E (0.53) KDM4EATML3MBTL1PGRPTPN1
SCHEMBL3810170 0.87 KDM4E (0.53) KDM4EATML3MBTL1PGRPTPN1
SCHEMBL12462123 0.87 KDM4E (0.42) KDM4EATML3MBTL1PGRHDAC4
SCHEMBL13629762 0.86 KDM4E (0.44) KDM4EATML3MBTL1PGRPTPN1
SCHEMBL10063570 0.86 KDM4E (0.44) KDM4EATML3MBTL1PGRPTPN1
SCHEMBL16268823 0.86 KDM4E (0.47) KDM4EATML3MBTL1PGRHDAC4
SCHEMBL12893320 0.86 KDM4E (0.47) KDM4EATML3MBTL1HDAC4AKR1C4
SCHEMBL14902278 0.86 KDM4E (0.41) KDM4EATML3MBTL1HDAC4AKR1C4
SCHEMBL13634179 0.84 KDM4E (0.40) KDM4EATML3MBTL1PGRHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9859505-B2 Charge-transporting molecular glass mixtures, luminescent molecular glass mixtures, or combinations thereof or organic light emitting diodes and other organic electronics and photonics applications MOLECULAR GLASSES, INC. (US) 2018-01-02 US disclosed
WO-2015129994-A1 NOVEL RED LIGHT-EMITTING IRIDIUM (III) COMPLEX COMPOUND CAPABLE OF BEING SOLUTION-PROCESSED AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 부산대학교 산학협력단 2015-09-03 WO disclosed
US-20150053894-A1 Charge-transporting Molecular Glass Mixtures, Luminescent Molecular Glass Mixtures, or Combinations Thereof for Organic Light Emitting Diodes and other Organic Electronics and Photonics Applications Molaire Consulting 2015-02-26 US disclosed
US-20150053894-A1 Charge-transporting Molecular Glass Mixtures, Luminescent Molecular Glass Mixtures, or Combinations Thereof for Organic Light Emitting Diodes and other Organic Electronics and Photonics Applications Molaire Consulting 2015-02-26 US disclosed
US-8546505-B2 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2013-10-01 US disclosed
US-8546505-B2 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2013-10-01 US disclosed
US-8546505-B2 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2013-10-01 US disclosed
US-8084935-B2 Comprises spin coated polyethylenedioxylthiophene/polystrene sulfonate and phosphorescent tris(2-phenylpyridine)iridium DAI NIPPON PRINTING CO., LTD. (JP) 2011-12-27 US disclosed
US-20110196104-A1 Norbornene-based copolymers with iridium complexes and exiton transport groups in their side-chains and use thereof GEORGIA TECH RESEARCH CORPORATION (US) 2011-08-11 US disclosed
US-20110196104-A1 Norbornene-based copolymers with iridium complexes and exiton transport groups in their side-chains and use thereof GEORGIA TECH RESEARCH CORPORATION (US) 2011-08-11 US disclosed
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2010-12-30 US disclosed
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2010-12-30 US disclosed
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2010-12-30 US disclosed
WO-2009080799-A2 CARBAZOLE-BASED HOLE TRANSPORT AND /OR ELECTRON BLOCKING MATERIALS AND /OR HOST POLYMER MATERIALS GEORGIA TECH RESEARCH CORPORATION (US) 2009-07-02 WO disclosed
US-20090153021-A1 LARGE-BANDGAP HOST MATERIALS FOR PHOSPHORESCENT EMITTERS WASHINGTON, UNIVERSITY OF (US) 2009-06-18 US disclosed
US-7105258-B2 Charge transport monomer, charge transport material, and process for producing the same DAI NIPPON PRINTING CO., LTD. (JP) 2006-09-12 US disclosed
US-20050129980-A1 Organic electroluminescent element and display panel using said element DAI NIPPON PRINTING CO., LTD. (JP) 2005-06-16 US disclosed
US-20050118521-A1 Charge transport monomer, charge transport material, and process for producing the same DAI NIPPON PRINTING CO., LTD. (JP) 2005-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090153021-A1 LARGE-BANDGAP HOST MATERIALS FOR PHOSPHORESCENT EMITTERS IQGAP1, SGTA, DPAGT1 KDM4E 2906/4885ATM 3252/4885L3MBTL1 2082/4885
US-20050118521-A1 Charge transport monomer, charge transport material, and process for producing the same TSPO, SLC43A1, CACYBP KDM4E 2036/4885ATM 3160/4885L3MBTL1 3845/4885
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials OCIAD1, HPD, OXA1L KDM4E 4260/4885ATM 4224/4885L3MBTL1 1007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.