Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CTSD | P07339 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13163089 | 0.95 | ALDH1A1 (0.61) | ALDH1A1RAB9ANPC1LMNAKDM4E | |
| SCHEMBL31542074 | 0.92 | ALDH1A1 (0.65) | ALDH1A1KDM4EHTTGAAMEN1 | |
| SCHEMBL1670667 | 0.92 | ALDH1A1 (0.65) | ALDH1A1KDM4EHTTGAAMEN1 | |
| SCHEMBL14511306 | 0.87 | ALDH1A1 (0.57) | ALDH1A1RAB9ANPC1LMNAKDM4E | |
| SCHEMBL4959067 | 0.87 | ALDH1A1 (0.59) | ALDH1A1RAB9ANPC1KDM4EHTT | |
| SCHEMBL4959078 | 0.87 | ALDH1A1 (0.59) | ALDH1A1RAB9ANPC1KDM4EHTT | |
| SCHEMBL13162530 | 0.87 | ALDH1A1 (0.59) | ALDH1A1RAB9ANPC1KDM4EHTT | |
| SCHEMBL15888546 | 0.86 | ALDH1A1 (0.58) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13634257 | 0.86 | ALDH1A1 (0.58) | ALDH1A1RAB9ANPC1KDM4EMEN1 | |
| SCHEMBL13634235 | 0.85 | ALDH1A1 (0.56) | ALDH1A1RAB9ANPC1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |