Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CTSD | P07339 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542074 | 0.92 | ALDH1A1 (0.65) | ALDH1A1CTSDL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL1670667 | 0.92 | ALDH1A1 (0.65) | ALDH1A1CTSDL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL4959078 | 0.86 | ALDH1A1 (0.59) | ALDH1A1CTSDL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL4959067 | 0.86 | ALDH1A1 (0.59) | ALDH1A1CTSDL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL13162530 | 0.86 | ALDH1A1 (0.59) | ALDH1A1CTSDL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL13163089 | 0.86 | ALDH1A1 (0.61) | ALDH1A1CTSDL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL15888546 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CTSDL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL13634257 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CTSDL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL13634180 | 0.85 | ALDH1A1 (0.61) | ALDH1A1CTSDL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL13162533 | 0.84 | MAPT (0.60) | ALDH1A1CTSDL3MBTL1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |