Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634281 | 1.00 | MEN1 (0.38) | MEN1KMT2ATHRBLMNA | |
| SCHEMBL3553091 | 0.81 | THRB (0.38) | MEN1KMT2ATHRBLMNA | |
| SCHEMBL10278352 | 0.81 | THRB (0.38) | MEN1KMT2ATHRBLMNA | |
| SCHEMBL3436066 | 0.75 | THRB (0.40) | MEN1KMT2ATHRB | |
| SCHEMBL18674636 | 0.75 | MEN1 (0.39) | MEN1KMT2ALMNA | |
| SCHEMBL13634344 | 0.75 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL3436042 | 0.74 | RAB9A (0.49) | MEN1KMT2ATHRBLMNA | |
| SCHEMBL15888548 | 0.74 | RAB9A (0.49) | MEN1KMT2ATHRBLMNA | |
| SCHEMBL13662109 | 0.73 | MEN1 (0.56) | MEN1KMT2ALMNA | |
| SCHEMBL18674630 | 0.72 | PIK3CD (0.37) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |