Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | SCD | O00767 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | OGA | O60502 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634303 | 0.85 | HRH3 (0.48) | HRH3SCDSMN1; SMN2ARMAPT | |
| SCHEMBL27811805 | 0.80 | SCD (0.41) | HRH3SCDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3559247 | 0.80 | HRH3 (0.55) | HRH3SMN1; SMN2POLBL3MBTL1DPP4 | |
| SCHEMBL13634230 | 0.80 | HRH3 (0.55) | HRH3SCDSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL2772627 | 0.80 | SCD (0.50) | HRH3SCDOGAEPHX2 | |
| SCHEMBL2770250 | 0.79 | HRH3 (0.58) | HRH3SCDSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL27868481 | 0.77 | HRH3 (0.48) | HRH3SCDNPC1HTTRAB9A | |
| SCHEMBL27811807 | 0.77 | HRH3 (0.44) | HRH3SCDSMN1; SMN2NPC1LMNA | |
| SCHEMBL13634292 | 0.76 | HRH3 (0.52) | HRH3SMN1; SMN2POLBL3MBTL1DPP4 | |
| SCHEMBL10136842 | 0.75 | HRH3 (0.49) | HRH3SMN1; SMN2POLBL3MBTL1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |