Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | OGA | O60502 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634365 | 0.92 | HRH3 (0.47) | HRH3L3MBTL1PIK3CAMTORDPP4 | |
| SCHEMBL13634230 | 0.86 | HRH3 (0.55) | HRH3L3MBTL1DPP4SMN1; SMN2LMNA | |
| SCHEMBL13634414 | 0.85 | HRH3 (0.40) | HRH3L3MBTL1DPP4SMN1; SMN2LMNA | |
| SCHEMBL3559247 | 0.83 | HRH3 (0.55) | HRH3L3MBTL1DPP4SMN1; SMN2LMNA | |
| SCHEMBL13634346 | 0.80 | HRH3 (0.47) | HRH3L3MBTL1SMN1; SMN2LMNAMAPT | |
| SCHEMBL10136842 | 0.78 | HRH3 (0.49) | HRH3L3MBTL1DPP4SMN1; SMN2LMNA | |
| SCHEMBL13162288 | 0.78 | HRH3 (0.61) | HRH3L3MBTL1SMN1; SMN2LMNAOGA | |
| SCHEMBL13634185 | 0.78 | HRH3 (0.50) | HRH3L3MBTL1DPP4SMN1; SMN2MAPT | |
| SCHEMBL12988798 | 0.77 | HRH3 (0.52) | HRH3L3MBTL1DPP4SMN1; SMN2LMNA | |
| SCHEMBL13634296 | 0.76 | HRH3 (0.49) | HRH3L3MBTL1DPP4SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |